History: New Orleans Saints vs. Buffalo Bills
The Saints lead the all-time series 7-4, holding a five-game winning streak against the Bills. New Orleans has posted a 3-3 mark in home contests played against Buffalo, winning in three different facilities; Tulane Stadium (1973), San Antonio's Alamodome (2005) and the Mercedes-Benz Superdome (2013). Kamara had the first 100-yard rushing game of his four-year career against the Bills when he carried 12 times for 106 yards with one touchdown in a 47-10 Saints win at Buffalo's New Era Field on November 12, 2017.
Players and Coaches to Know
Buffalo Bills
Head Coach: Sean McDermott
Quarterback: Josh Allen
Key Position Players: RB Devin Singletary, WR Emmanuel Sanders, WR Stefon Diggs
New Orleans Saints
Head Coach: Sean Payton
Quarterback: Jameis Winston & Taysom Hill
Key Position Players: RB Alvin Kamara, WR Michael Thomas