Highlights | Buffalo Bills at New Orleans Saints 2021 NFL Week 12 | NewOrleansSaints.com

New Orleans Saints linebacker Kwon Alexander comes up with the finger-tip interception off Josh Allen and the Bills on Thursday Night Football in Week 12 of the 2021 NFL season. Saints senior writer John DeShazier breaks it down in this week's Expert Analysis presented by Microsoft Surface.

Buffalo Bills at New Orleans Saints game highlights from Thanksgiving night on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints center Erik McCoy's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints defensive end Cameron Jordan's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kwon Alexander's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints head coach Sean Payton's postgame interview following the Saints' Thanksgiving night loss to the Buffalo Bills on Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian finds tight end Nick Vannett in the back of the end zone for the touchdown against the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints quarterback Trevor Siemian stands strong in pocket to deliver 24-yard catch and run to Lil'Jordan Humphrey  against the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

Go inside Caesars Superdome for Thursday Night Football as a full capacity crowd give thanks to Drew Brees as he returns the favor on Thanksgiving during halftime of the New Orleans Saints' game vs the Buffalo Bills in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kwon Alexander intercepts a pass thrown by Buffalo Bills quarterback Josh Allen right before halftime on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

Harry Connick Jr., Carli Lloyd, Matthew McConaughey, Vince Vaughn, and Wendell Pierce reminisce about the impact of New Orleans Saints legend Drew Brees and his lasting legacy on and off the field.

New Orleans Saints cornerback Bradley Roby slips around the receiver for the interception off Josh Allen and the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Kaden Elliss goes unblocked to sack Buffalo Bills quarterback Josh Allen on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints defensive Carl Granderson speeds around the edge and finishes the sack from the ground against Josh Allen and the Buffalo Bills on Thanksgiving night for Thursday Night Football in week 12 of the 2021 NFL season.

New Orleans Saints linebacker Demario Davis gets the Saints hyped up ahead of their game against the Buffalo Bills on Thursday Night Football onn Thanksgiving Night in week 12 of the 2021 NFL season with the Saints Pregame Huddle.

Get hype for the New Orleans Saints' Week 12 Thursday Night Football game against the Buffalo Bills on Thanksgiving day at 7:20 p.m. on NBC.

Learn more about New Orleans Saints safety PJ Williams in his 2021 Player Spotlight presented by Microsoft Teams.

New Orleans Saints Coach Sean Payton met with the media Wednesday, Nov. 24 to talk about Thursday's game against the Buffalo Bills in the Caesars Superdome.

New Orleans Saints tight end Nick Vannett met with the media Wednesday, Nov. 24 ahead of Thursday's home game against the Buffalo Bills.

New Orleans Saints linebacker Demario Davis met with the media Wednesday, Nov. 24 one day before the team's Thanksgiving night game against the Buffalo Bills.

New Orleans Saints quarterback Trevor Siemian post-practice interview ahead of the Saints' week 12 game against the Buffalo Bills on Thursday Night Football during the 2021 NFL season.

New Orleans Saints linebacker Kwon Alexander post-practice interview ahead of the Saints' week 12 game against the Buffalo Bills on Thursday Night Football during the 2021 NFL season.

New Orleans Saints offensive lineman James Hurst post-practice interview ahead of the Saints' week 12 game against the Buffalo Bills on Thursday Night Football during the 2021 NFL season.

New Orleans Saints defensive end Cameron Jordan post-practice interview ahead of the Saints' week 12 game against the Buffalo Bills on Thursday Night Football during the 2021 NFL season.