 - With the loss, the New Orleans Saints fall to 10-3 on the season and 5-2 at home. New Orleans returns to action Monday, Dec. 16 when it hosts the Indianapolis Colts in the Mercedes-Benz Superdome. Kickoff is set for 7:15pm CT on ESPN.

- With the loss, New Orleans' all-time record against the 49ers falls to 26-48-2. Coach Sean Payton's all-time record against San Francisco drops to 6-3 and 3-3 at home and Payton falls in his first career match-up with 49ers Coach Kyle Shanahan.

- The Saints and 49ers combined for 55 points and eight touchdowns in the first half, both highs in any game this season. The last time two teams combined for 55 first half points was Week 1 of the 2018 season (New Orleans and Tampa Bay combined for 55 points) and the last time two teams combined for eight first half touchdowns was Week 10 of the 2010 season (Washington and Philadelphia combined for eight touchdowns).

- New Orleans amassed 465 total yards, their highest output since Oc. 27 vs. Arizona, including 349 passing yards and 116 yards on the ground. The Saints scored touchdowns on each of their first four drives for the first time since Oc. 8, 2018, when they defeated the Washington Redskins 43-19.

 - New Orleans held San Francisco running backs Matt Breida and Raheem Mostert to 54 yards and 69 yards, respectively, and extend its streak to 39 consecutive games, including regular and postseason play, without allowing a 100-yard rusher.

• New Orleans surrendered a season-high 516 yards of offense to San Francisco, including 354 passing yards and 162 rushing yards.

 - Quarterback Drew Brees was 29-of-40 passing for 349 yards. Brees threw for five touchdowns for the 10th time in his career and first time since throwing seven against the New York Giants on November 1, 2015.

 - Brees now is tied with Peyton Manning with 35 career games with at least four touchdown passes for first in NFL record books, ahead of Tom Brady (29, entering Sunday's game vs. Kansas City).

 - Brees also rushed for his 19th touchdown as a member of the Saints on a one-yard run in the second quarter. The score breaks a tie with former Saints signal-caller Archie Manning for the most rushing touchdowns by a quarterback in club history and was his 23rd overall in his 19-year career.

 - With 134 yards on 11 receptions, receiver Michael Thomas set a franchise record for receiving yards in a season with 1,424 yards so far this season, breaking his own record of 1,405 set last season. Thomas' season total moves to 121 receptions, surpassing Marvin Harrison's 118 for the most receptions through the first 13 games of a season.

 - Running back Alvin Kamara surpassed 2,000 yards receiving for his career with his 6-yard reception with 10:32 to play in the second quarter. Kamara becomes just the fourth NFL running back to amass 2,000 yards rushing and 2,000 yards receiving in their first three seasons, joining Christian McCaffrey, Roger Craig, and Herschel Walker. Kamara finished with 25 rushing yards on and 18 yards on four receptions. Kamara's third quarter fumble was the Saints' first offensive fumble lost of the season. 

• Running back Latavius Murray finished with 67 yards on nine carries. His 9.9 yards per carry was his highest average this season.

 - Playing in his 184th career game, receiver Ted Ginn Jr. recorded four receptions for 50 yards, both highs since recording seven receptions for 101 yards on opening night vs. Houston, Sept. 9. 

• Tight end Josh Hill scored his second touchdown of the season on a 3-yard reception with 14:57 to play in the second quarter, marking his first season with multiple scoring grabs since 2015. Hill finished with two receptions for four yards. 
• Receiver Deonte Harris recorded a reception and rushing attempt for the first time in his career, finishing with 13 receiving yards on the one reception and eight rushing yards on one rush. Harris made an impact in the return game, recording kickoff
  returns of 31, 51, and 21 yards and a punt return of 25 yards, all of which set up Saints first half touchdowns.

 - Receiver Tre'Quan Smith scored the Saints' final touchdown on an 18-yard reception from Brees with 53 seconds to play. Smith has now scored three touchdowns this season, two coming within the last three games.

 - Safety Vonn Bell recorded his first solo sack of the season, taking down 49ers quarterback Jimmy Garoppolo with 2:38 left in the fourth quarter. He finished with a team-leading 12 stops, and now has 86 tackles in 2019. Bell's three stops away from setting a career-high. 

• Linebacker Demario Davis recorded his third sack of the season, and second in the last three weeks. Davis finished with seven tackles, moving his season total to 95 stops. With five more tackles, Davis will have 100 stops for the third consecutive season and sixth time in his career. 
• Linebacker Craig Robertson recorded the 10th interception of his career, picking off Garoppolo with 13:36 to play in the third quarter. The interception was Robertson's first since Dec. 31, 2017 when he picked off Jameis Winston in the final game of 2017. Robertson added eight tackles and one pass defense on the afternoon.

 - Defensive tackle Mario Edwards Jr. recorded his second sack of the season, both coming in the last three weeks, taking down Garoppolo with 4:42 to play in the third quarter.

- Kicker Wil Lutz has now converted 14 consecutive field goals, connecting on a 55-yarder with 12:41 to play in the third quarter, a 48-yarder with 4:56 to play in the third quarter. Lutz has now converted a league-leading 29 field goals this season.

 - Punter Thomas Morstead punted once for 45 yards. Morstead appeared in his 171st career game, moving into a tie with Wayne Martin for eighth place on the club's all-time games played list.

 - Before leaving the game in the second quarter with a concussion, tight end Jared Cook scored multiple touchdowns for the fourth time in his career. Cook finished twith two receptions for 64 yards and the two scores. Cook now has six touchdowns this season, matching a career-high set last year as a member of the Oakland Raiders.

 - After failing to score on their opening possession in any of their first eight games, the Saints have now scored on their opening possession for four straight weeks. Cook's 38-yard touchdown reception capped off a Saints nine-play, 73-yard drive that used the first 3:26. Cook scored again on the Saints' second possession, marking the first time this season New Orleans has opened the game with touchdowns on both of its first two possessions.

- The Saints' extended their streak to 285 consecutive games without having been shut out, dating to a 26-20 victory at Tampa Bay on Sept. 6, 2002. The streak is the longest running streak in the NFL and fourth longest in league history.